Colistin-containing cement spacer for treatment of experimental carbapenemase-producing Klebsiella pneumoniae prosthetic joint infection
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چکیده
منابع مشابه
Colistin heteroresistance in carbapenemase-producing Klebsiella pneumoniae.
Sir, Klebsiella pneumoniae is an important pathogen that causes severe and life-threatening infections. Most isolates demonstrate resistance to various antimicrobial agents. Carbapenems have been widely used to treat serious infections with multidrug-resistant K. pneumoniae. However, the increasing use of these compounds has led to the emergence of carbapenem-resistant isolates via acquired gen...
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The continuing emergence of infections due to multidrug resistant bacteria is a serious public health problem. Klebsiella pneumoniae, which commonly acquires resistance encoded on mobile genetic elements, including ones that encode carbapenemases, is a prime example. K. pneumoniae carrying such genetic material, including both blaKPC and genes encoding metallo-β-lactamases, have spread globally...
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et al. Quantitative nucleic acid sequence-based assay as a new molecular tool for the detection and quantifi cation of Leish-mania parasites in skin biopsies.ther observations on clinical, histopatho-logical, and immunological features of borderline disseminated cutaneous leish-maniasis caused by Leishmania (Leish-mania) amazonensis. leishmaniasis due to Leishmania (Leish-mania) amazonensis in ...
متن کاملInvestigating the Resistance of Klebsiella Pneumoniae Clinical Isolates Producing Carbapenemase and ESBL Enzymes to Colistin and Fosfomycin Antibiotics
Introduction: A Klebsiella pneumoniae bacterium, which is the most important species of the Klebsiella genus, mainly causes hospital infections. Moreover, it has a high resistance to most of the available antibiotics, which has caused concern among doctors all over the world. Therefore, the amount of antibiotic resistance and the effect of these antibiotics on Klebsiella pneumoniae isolates pr...
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To the Editor: Until a few years ago, the most frequent microbiologi-cally documented cause of severe bloodstream infections among patients with hematologic malignancies was gram-positive bacteria (1). However , over the years, gram-negative bacteria have become the main infectious cause of death among patients with hematologic malignancies, and rates of different phenotypes associated with ant...
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ژورنال
عنوان ژورنال: International Journal of Antimicrobial Agents
سال: 2019
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2019.07.009